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Web Changes

This is where we'll announce the most recent additions to our web site. If you've visited us before and want to know what's changed, take a look here first.

March 20, 2008

Issue with Rugloop rev. 11.47-11.76
An erroneous registration of the patient's gender is observed in certain RugloopII versions. Female registrations are ignored, and converted into 'male' patients. Therefore, you will need to recover gender information from your own study documentation, if needed.  
This issue has no side-effects for calculation of PK parameters EXCEPT for ALFENTANIL. Please contact us to work out a solution If you have been using Alfentanil in TCI with these Rugloop versions. 

The RugloopII versions suffering this defect have been identified as all versions from 11.47 on. It was resolved in release 11.77. Please contact Demed for download & installation instructions for this version.  

We are very sorry for any inconvenience this may have caused. 

October 30, 2008

Excel Macro updated 
A number of issues in the Excel processing was solved. The new macro can be freely downloaded here.  

September 30, 2008

Aspect Medical systems Bilateral VISTA is supported 

awaited for a long time, finally arrived: the combination of Rugloop capturing the complete bilateral information from the Aspect Medical Systems VISTA monitor is commercially available. Please contact Demed for an upgrade to RugloopII 11.65 or better, AND, your Aspect Medical representative for

* the new BIS VISTA Monitoring System with Bilateral sensor
* or an update of your existing VISTA Monitoring System to Application Revision 3.00 (Monitor Revision 3.01)

May 28, 2008

Excel Macro available 

For users struggling with the Rugloop data files, an excel macro was developed to simplify parsing multiple datalines in a single file. The macro can be freely downloaded here.  
We are working on a similar approach for Matlab import functionality. 

New Labgrab available 

The latest Labgrab is available (2.17) and can be downloaded here.  This version has a number of issues fixed, no specific added functionality.

December 15, 2007

RugloopII update

RugloopII release 11.46 is available, with another set of new drivers. The following devices are now supported: 

  • Aspect VISTA + wave capturing
  • Philips  Intellivue monitors + wave capturing, both through serial line and through ethernet connection
  • Hospira Sedline monitor  + wave capturing
  • INVOS Somanetics monitor 

For an extensive list of supported devices, please check here

Labgrab  update

Labgrab received a number of modifications to further simplify reading in non-Rugloop generated ascii files. 

For more information, please contact us. 

December 23, 2006

RugloopII update

RugloopII release 11.27 is available. 

This update will facilitate finding the right serial port: Rugloop will now only show the physically available ports for selection. 
This should considerably speed up finding the right port.  
Other modifications are: 

  • development for GCP compliance is finished & was tested. 
  • Hospira Sedline monitor is supported 
  • Philips  Intellivue monitors (MP70/90) are supported 
  • A2000 column naming: apparently Rugloop would sometimes still mix up the column names for the captured BIS algorithms. This has been fixed. 

The new release can be downloaded & installed by the registered users. 
An updated list of the currently supported devices can be found here

Furthermore, we are still working on the Rugloop tags, which will be available soon ! These will allow automated detection of the port being used !
Also, the new BIS VISTA monitor driver development is in the pipeline, for Q1 2007, as is the support of wave capturing from the Philips Intellivue monitor. 

Check here for more news soon! 

August 7, 2006

The new Labgrab has arrived 

Since its first release now 3 years ago, Labgrab has had many useful comments from users. A majority of them have been integrated in the new release, 2.08, which is available now. The new release can be downloaded & installed by the registered users. Trial licenses are available upon e-mail request. (

Feb 10th, 2006

Rugloop tags relieve the burden of finding the right serial port ....  

Connecting multiple monitors with Rugloop can, sometimes, be a nightmare. The solution is in sight with the Rugloop tags! 
A Rugloop tag is a small hardware device to be mounted inbetween the serial port and the monitor cable. The tag is visibly labeled with the monitor name & type. In software, Rugloop will automatically search for the serial port with the correct tag, and connect to the monitor behind it. So no more fooling around with COM settings when another study has been using the same hardware setup ! 

The tags are currently in development ! Find out more on this site soon ! 

Philips intellivue driver is in development.  

The development of the Philips intellivue driver was started. The driver will be available soon ! 

Jan 25th, 2006

GCP compliance. 

Good Clinical Practice (GCP) is an international ethical and scientific quality standard for designing, recording and reporting trials that involve the participation of human subjects. Compliance with this standard provides public assurance that the rights, safety and well being of trial subjects are protected, consistent with the principles that have their origin in the Declaration of Helsinki, and that the clinical trial data are credible.

We are in the process of integrating methods into RugloopII(c) to facilitate research according to GCP guidelines when using Rugloop. These methods include required login procedure, studies registration, and detailed pdf-based logs.  

For more information, see RugloopII© GCP compliance

August 18, 2005

Demed proudly presents... the Rugloop video module. 

Imagine that you could synchronize operating theatre events captured on tape with your sampled case data... now you can ! 
Rugloop was extended with an option allowing to capture video from any video source connected to the PC. The video is overlaid with the current PC time and relative case time before it is written to file. The output file is a standard avi-file that can be played with any media player, and that has both times displayed.

See RugloopII© video capture

July, 2005

* a new Rugloop version is available (11.08). This supports the newest A2000 monitor, and has a bug fix for the Philips/Agilent/HP CMS/Merlin/V24/V26 monitor series. 
* A new FAQ was added concerning Rugloop number format. 

April, 2005

Demed has attended the AMCA workshop where we presented 2 topics:
Pitfalls in creating commercial devices from theoretical TCI concepts. 
A Bayesian approach for online estimation of PD parameters
Abstracts & slides of the presentations can be found at  the links above. 

A new FAQ (Q5/A5) was added about issues when connecting to the A2000 monitor. 

December 20, 2004


one potential source of troubles with RugloopII TCI is the option of purging the system. If a user would accidentally press OK, the system would deliver the drug at 200ml/h. An update was made RugloopII(c) to accommodate for this: the new RugloopII(c) requires you to keep on pushing the 'purge' button while purging. We believe this is an IMPORTANT SAFETY UPGRADE that all Rugloop TCI users should install. So, if you are a Rugloop TCI user, please contact us for instructions on how to upgrade your version with this safety improvement. (Rugloop 10.00)

July 10, 2004

RugloopII(c) now also supports WAVES CAPTURING for the Aspect A2000, AS3 / S5 monitor. click here for more information

July 1, 2004

The RugloopII driver for the Siemens SC5000 6000 7000 8000, 9000 is now ready for beta - testing. Interested testers please mail.   

June 08, 2004

Euroanesthesia news: PocketPC users: click here 

May 10, 2004

RugloopII used as foundation for the calculation engine in the Asena (R) PK syringe pump. More on Alaris Medical Systems website 

April 14, 2004

RugloopII, rev. 9.82 supports the new Dräger Zeus anesthesia machine, as well as an updated version of the Julian and Primus devices. 

March 3, 2004

Another update: RugloopII (rev. 9.80) is released:

  • a few bug fixes (the application could lock the system when selecting an unavailable COM port)

  • infusion devices can be disabled 

  • the syringe drug concentration can be adjusted  

A new component was added targeted to improve research: the STOPWATCH component. This component can load a series of events upon startup; whenever the case time is about to cross such an event's time, a countdown is started. When the event has elapsed, it is added to a list until it is confirmed by the user. Upon confirm, a log is added to the standard Rugloop log indicating event time, confirm time, and event notification. The events are loaded from a standard comma-separated file, enabling you to create your own set of events


Februari 1, 2004

It took a long time .... but the new RugloopII (rev. 9.78) is released:


  • support for capturing waves from the connected general-purpose monitors 

  • veterinary applications: support for capturing analog input values using  B&B electronics UD128A8D 6-channel A/D converter

  • support for 2 new drugs: dexmedetomidine & midazolam - see also the spreadsheets on the 'downloads' page.   

Januari 10 , 2003

The 'downloads' page has been updated with a lot of new spreadsheet models. 

December 15 , 2002

The Dräger Julian ventilator is now supported by the Rugloop platform. 

September 27, 2002

IMPORTANT NEWS! Rugloop, TCI, CE & research  - read our new evolutions here

September 15, 2002

The RugloopII driver for the GE MEdical systems Marquette Solar monitor is now ready for beta - testing. Interested testers please mail.   

August 1, 2002

Released RugloopII  rev. 9.64. 
 Features added:
* comment buttons (more than 20 !)? FULLY re-configurable while start button is not pushed yet. 
* settings (com port etc. ) now stored in registry
* cancel button in configuration dialog
* Philips CMS monitor series now fully supported.

December 27, 2001
Launch of the DEMED Website